Interleukin-17A Inhibitor–induced Crohnʼs Disease/Behçetʼs Disease–like Lesions
نویسندگان
چکیده
منابع مشابه
Analysis of Interleukin 17A in periapical abscess and granuloma lesions.
Interleukin 17A (IL-17A) is a proinflammatory cytokine responsible for the initiation and propagation of inflammation. One of its actions is the recruitment of neutrophils to the site of infection. The aim of this study was to investigate whether there is association between IL-17A expression and neutrophil infiltration in periapical abscesses and periapical granulomas, as well as to find which...
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INTRODUCTION Morphea is a disease included in the group of scleroderma type autoimmune diseases. Interleukin (IL)-17A may play a role at every stage of its pathogenesis. The study aimed at evaluation of IL-17A and IL-23 (as the main cytokine which is supposed to stimulate and maintain synthesis of IL-17) in pathogenesis of morphea. MATERIAL AND METHODS The studies were performed on 41 blood s...
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It is now established that an excessive and sustained mobilisation of neutrophils is a hallmark of several chronic inflammatory lung disorders, including severe obstructive lung disease. This article reviews evidence that the cytokine interleukin (IL)-17A is a major orchestrator of sustained neutrophilic mobilisation. Current evidence suggests that IL-17A is produced by T-lymphocytes, and that ...
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ژورنال
عنوان ژورنال: Inflammatory Bowel Diseases
سال: 2017
ISSN: 1078-0998
DOI: 10.1097/mib.0000000000001142